Nova Clinic is glad to offer their patients a genetic screening for fetal chromosomal mutations through the analysis of the mother’s blood sample with the help of next-generation sequencing (NGS) technique.
Non-invasive genetic test helps detect most wide-spread chromosomal pathologies:
- Down’s syndrome
- Edwards' syndrome
- Patau's syndrome
- Klinefelter's syndrome
- Turner's syndrome
A patient receives the geneticist’s medical conclusion as well as the results of the test.
Advantages of non-invasive prenatal test
There is no contact with an embryo’s membrane, which, otherwise, may cause miscarriages or other complications. A venous blood sample collected from a woman is quite enough to perform the test. All these are safe both for the mother and the fetus.
- High accuracy
The non-invasive test uses fetal DNA, which, unlike an ultrasound and a biochemical screening, is a direct diagnostic technique with accuracy up to 99,9%. It should be also noted that the percentage of inaccurate (false-positive) results is inferior than 0,1% .
The test can be recommended to all pregnant women who want to obtain additional information on their babies’ health condition. However, the test is usually recommended to women running a high risk of having a baby with chromosomal mutations:
- when a women is over 35
- when a man is over 42
- ultrasound or a biochemical screening indicate to a high risk of developing a chromosomal pathology
- balanced chromosomal alteration has been found in one of the parents
Restrictions on a non-invasive prenatal diagnosis
- pregnancy term is less than 10 weeks
- multifetal pregnancy
- blood transfusion (over two recent years)
- organ transplant operations or treatment with stem cells
- oncological diseases
- IVF with donor egg cells
Non-invasive prenatal diagnosis includes the following steps
- collection of a venous blood sample
- blood sample screening for fetal chromosomal pathologies
- calculation of an individual risk of having a baby with chromosomal mutations
- geneticist’s medical conclusion on the mother’s health condition